Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.6
USERS' SCORE
Good
Based on 3 Reviews
8.4
Top Medical Research Studies
9
We sought to understand the role of vitamin D3 supplementation in alleviating chronic low back pain (CLBP). In a single-arm, open-label study at a tertiary care hospital, we worked with 68 patients suffering from CLBP for at least three months, each demonstrating a significant pain level on a visual scale alongside low vitamin D levels.
Participants received 60,000 IU of vitamin D3 weekly for eight weeks. We tracked pain intensity and functional disability at various stages: at the outset, and then at two, three, and six months post-supplementation. Notably, we witnessed a remarkable increase in vitamin D levels from an average of 12.8 ng/mL to 36.07 ng/mL in those eight weeks, with 66% of participants achieving normal vitamin D levels.
The benefits didn’t stop there. Patients reported a significant drop in their pain scores at all follow-up periods, improving from 81 to 36 on the scale. Functional ability also saw enhancement over time, proving the positive influence of vitamin D3 on both pain and everyday activities.
Overall, our findings suggest that vitamin D3 supplementation can be an effective avenue for improving pain intensity and functionality in individuals with low back pain, warranting further investigation through controlled clinical trials.
Participants received 60,000 IU of vitamin D3 weekly for eight weeks. We tracked pain intensity and functional disability at various stages: at the outset, and then at two, three, and six months post-supplementation. Notably, we witnessed a remarkable increase in vitamin D levels from an average of 12.8 ng/mL to 36.07 ng/mL in those eight weeks, with 66% of participants achieving normal vitamin D levels.
The benefits didn’t stop there. Patients reported a significant drop in their pain scores at all follow-up periods, improving from 81 to 36 on the scale. Functional ability also saw enhancement over time, proving the positive influence of vitamin D3 on both pain and everyday activities.
Overall, our findings suggest that vitamin D3 supplementation can be an effective avenue for improving pain intensity and functionality in individuals with low back pain, warranting further investigation through controlled clinical trials.
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9.5
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
Read More
9.5
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
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Most Useful Reviews
7.5
Pain relief noted
80 people found this helpful
Bone Strength. I found this supplement after some research and liked that its calcium comes from a plant source, along with magnesium, strontium, vitamin D, and vitamin K, which all work together to strengthen bones. Taking them separately can lead to imbalances. Six years ago, my bone density showed -2.5 (osteoporosis) in my hips and back, accompanied by constant aches. Within six months of starting this supplement, my knee pains stopped completely. I have had bone density tests every two years since. My bone density has improved from -2.5 to -1.4, which is reassuring, especially at my age of 74.
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9
Improved bone density
30 people found this helpful
This stuff works! Three years ago, I was borderline osteoporosis and awaiting hip replacement surgery for excruciating back pain. I had lost 3.5" in height. My doctor advised against osteoporosis drugs, so I researched bone-building supplements and chose New Chapter Bone Strength. Since taking it religiously, my recent bone density scan showed improvement; my doctor was over the moon about the results. I've only been able to exercise recently, so I credit this product for my excellent results. It's an exceptional supplement that I highly recommend.
Read More
9
Strengthened bones
4 people found this helpful
Why I love this product? I have not used it in about four years, but if this is as good as it was, I had been told I had osteoporosis. For three years, I took this product, and the pain left. When I had a bone density test, there was no indication of osteoporosis. Now at 73 years old, I shouldn't have stopped using this bone support. I'm starting back now, trying to get back to exercising. We shall see if this helps strengthen my bones again, although I have not had a test yet. I will continue with this product unless they have changed it or are using lesser quality ingredients.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 30 Researches
7.6
- All Researches
9.5
We observed a fascinating case involving a male in his 40s who experienced persistent inflammatory back pain for three months. Despite having a negative test for HLA-B27, a marker often associated with axial spondyloarthritis, clinical assessments suggested possible underlying issues.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
The clinical investigation led to an MRI, which confirmed bilateral symmetrical sacroiliitis. Interestingly, further tests showed he had very low vitamin D levels along with elevated parathyroid hormone—indicating a possible deficiency impacting his condition.
After starting treatment with vitamin D alongside nonsteroidal anti-inflammatory drugs (NSAIDs), he experienced notable relief from his symptoms. His condition improved significantly, and follow-up tests indicated that his vitamin D levels had normalized.
This case demonstrates the potential benefits of vitamin D in managing back pain, especially when classical markers are inconclusive. It highlights how a thorough diagnosis can reveal interconnected health issues and improve treatment outcomes.
Read More
9.5
We observed a rare condition known as pregnancy-associated osteoporosis, which affected a 38-year-old woman after she gave birth. Just a month postpartum, she experienced sudden back pain due to four vertebral fractures, and her bone density was notably low, especially in the spine.
While the patient's biochemical tests were largely normal, we noted some concerning markers, including elevated urinary deoxypyridinoline and slightly reduced levels of serum vitamin D3. To address her symptoms and improve her bone health, a combination therapy consisting of neridronate, calcium, and cholecalciferol (vitamin D3) was initiated.
Encouragingly, after one month on this treatment, she reported being pain-free. Moreover, a follow-up bone density scan after six months indicated a significant improvement in her bone density in both the spine and hip areas. This suggests that while neridronate played a crucial role, it's also important to recognize the potential benefits of vitamin D3 within this treatment regimen. However, since the effects were part of a combination therapy, we cannot isolate the specific impact of vitamin D3 on back pain alone.
While the patient's biochemical tests were largely normal, we noted some concerning markers, including elevated urinary deoxypyridinoline and slightly reduced levels of serum vitamin D3. To address her symptoms and improve her bone health, a combination therapy consisting of neridronate, calcium, and cholecalciferol (vitamin D3) was initiated.
Encouragingly, after one month on this treatment, she reported being pain-free. Moreover, a follow-up bone density scan after six months indicated a significant improvement in her bone density in both the spine and hip areas. This suggests that while neridronate played a crucial role, it's also important to recognize the potential benefits of vitamin D3 within this treatment regimen. However, since the effects were part of a combination therapy, we cannot isolate the specific impact of vitamin D3 on back pain alone.
Read More
9.5
We explored the impact of various treatments, including vitamin D3, on severe back pain caused by pregnancy-related osteoporosis (PLO). In a significant case study, a 23-year-old woman experiencing debilitating back pain was treated after her first childbirth. By monitoring her bone mineral density, we noted low T- and Z-scores in her lumbar spine.
The treatment plan included teriparatide, calcium, and vitamin D3. While we observed substantial improvements in bone density and relief from pain, it’s important to note that the isolated effect of vitamin D3 is difficult to pinpoint due to its combination with other treatments.
Overall, while vitamin D3 plays a notable role alongside teriparatide in managing back pain linked to PLO, its individual effectiveness remains somewhat unclear.
The treatment plan included teriparatide, calcium, and vitamin D3. While we observed substantial improvements in bone density and relief from pain, it’s important to note that the isolated effect of vitamin D3 is difficult to pinpoint due to its combination with other treatments.
Overall, while vitamin D3 plays a notable role alongside teriparatide in managing back pain linked to PLO, its individual effectiveness remains somewhat unclear.
Read More
9.5
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.
Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Read More
9
We conducted a retrospective review to uncover how vitamin D treatment impacts back pain in individuals diagnosed with adult-onset hypophosphatemic osteomalacia. In our exploration, we found that eight patients, primarily experiencing widespread musculoskeletal pain, were assessed over a span from January 2011 to December 2019.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
Each patient presented with low phosphorus levels, elevated alkaline phosphatase, and indicative imaging results. Notably, back pain was reported as the most common complaint, along with muscle weakness in over half of the cases. Our findings highlighted the effectiveness of vitamin D in tandem with phosphorus supplementation, as all patients reported significant improvements in pain, muscle strength, and gait after receiving treatment.
Importantly, we noted that the specific diagnosis of each patient varied. In six cases, treatment was prompted by adefovir-induced Fanconi syndrome, while the remaining two patients had tumor-induced osteomalacia and light-chain nephropathy. This variation indicates the diverse etiologies of hypophosphatemic osteomalacia, further emphasizing the importance of targeted treatment based on individual needs.
In conclusion, our study suggests that vitamin D, especially when combined with phosphorus, plays a crucial role in alleviating back pain associated with this condition. By enhancing the understanding of the relationship between vitamin D treatment and back pain, we aim to shed light on effective management strategies for those suffering from similar symptoms.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Pain relief noted
80 people found this helpful
Bone Strength. I found this supplement after some research and liked that its calcium comes from a plant source, along with magnesium, strontium, vitamin D, and vitamin K, which all work together to strengthen bones. Taking them separately can lead to imbalances. Six years ago, my bone density showed -2.5 (osteoporosis) in my hips and back, accompanied by constant aches. Within six months of starting this supplement, my knee pains stopped completely. I have had bone density tests every two years since. My bone density has improved from -2.5 to -1.4, which is reassuring, especially at my age of 74.
Read More
9
Improved bone density
30 people found this helpful
This stuff works! Three years ago, I was borderline osteoporosis and awaiting hip replacement surgery for excruciating back pain. I had lost 3.5" in height. My doctor advised against osteoporosis drugs, so I researched bone-building supplements and chose New Chapter Bone Strength. Since taking it religiously, my recent bone density scan showed improvement; my doctor was over the moon about the results. I've only been able to exercise recently, so I credit this product for my excellent results. It's an exceptional supplement that I highly recommend.
Read More
9
Strengthened bones
4 people found this helpful
Why I love this product? I have not used it in about four years, but if this is as good as it was, I had been told I had osteoporosis. For three years, I took this product, and the pain left. When I had a bone density test, there was no indication of osteoporosis. Now at 73 years old, I shouldn't have stopped using this bone support. I'm starting back now, trying to get back to exercising. We shall see if this helps strengthen my bones again, although I have not had a test yet. I will continue with this product unless they have changed it or are using lesser quality ingredients.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
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- Bose S, Mohanasundaram K, Rajalakshmi KV, Perumal Kumaresan A, Simon J. An Unusual Mimic of Axial Spondyloarthritis: A Case Report. Cureus. 2024;16:e61441. 10.7759/cureus.61441
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- Dechsupa S, Yingsakmongkol W, Limthongkul W, Singhatanadgige W, Jitjumnong M, et al. Vitamin D Inadequacy Affects Skeletal Muscle Index and Physical Performance in Lumbar Disc Degeneration. Int J Mol Sci. 2023;24. 10.3390/ijms24043152
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- Ma Y, Wu X, Xiao X, Ma Y, Feng L, et al. Effects of teriparatide versus percutaneous vertebroplasty on pain relief, quality of life and cost-effectiveness in postmenopausal females with acute osteoporotic vertebral compression fracture: A prospective cohort study. Bone. 2020;131:115154. 10.1016/j.bone.2019.115154
- Pishgahi A, Dolatkhah N, Shakouri SK, Hashemian M, Amiri A, et al. Lower serum 25-hydroxyvitamin D3 concentration is associated with higher pain and disability in subjects with low back pain: a case-control study. BMC Res Notes. 2019;12:738. 10.1186/s13104-019-4768-0
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- Celenlioglu AE, Sir E, Ors-Yildirim N, Yildirim AK, Ince ME, et al. Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting. J Vasc Surg Venous Lymphat Disord. 2023;11:517. 10.1016/j.jvsv.2022.09.008
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- Huber D, Grafetstätter C, Proßegger J, Pichler C, Wöll E, et al. Green exercise and mg-ca-SO thermal balneotherapy for the treatment of non-specific chronic low back pain: a randomized controlled clinical trial. BMC Musculoskelet Disord. 2019;20:221. 10.1186/s12891-019-2582-4
- Yousef AA, Al-deeb AE. A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component. Anaesthesia. 2013;68:260. 10.1111/anae.12107
- Vormann J, Worlitschek M, Goedecke T, Silver B. Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain. J Trace Elem Med Biol. 2001;15:179.
- Liu J, Xu D, Liu L, Huang C, Guo Z, et al. Regular sling core stabilization training improves bone density based on calcium and vitamin D supplementation. BMC Musculoskelet Disord. 2023;24:815. 10.1186/s12891-023-06896-8
